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Transplantation of Autologous Adipose Derived Mesenchymal Stem Cells for Improvement of Quality of Life in Osteoarthritis Patients

Abstract:

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مقاله

عنوان نشریه:
International Journal of Musculoskeletal Pain Prevention
ISSN
جلد ۱، شماره ۳، صفحات ۱۰۹-۱۱۶
نویسندگان :
Hajar Shafaei
Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz. Hassan Bagernezhad
Radiology ward, Sina Hospital, Tabriz University of Medical Sciences. Hossein Soliemanlou
Orthopedic ward, Shahid Mahallati Hospital, Tabriz. Masoud Poureisa
Department of Radiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz.
Keywords
ASC Osteoarthritis Stem cell therapy Alleviation of pain
منابع مشابه

Background The aim of this clinical trial was the assessment of safety and efficacy of submocosal and periurethral injections of peripheral blood derived autologous stem cells along with platelets, and focused on outcome for six months. Methods An open, prospective study was conducted on 10 patients presenting with stress urinary incontinence. At the baseline (pre-operative), 1, 3 and 6 mont...

The stem cells can be considered as the miracle of creation, because, they are a major reservoir of the bioactive factors, molecules and cells. These reservoir cells play a major role in development and growth of the tissues and organs. Regardless of the differences in differentiation capacity of embryonic and adult stem cells, both the cells are rich sources of stem cells with therapeutic appl...

Osteoarthritis (OA) is a prevalent chronic disease impacting on quality of life and has societal and economical burden increasing with age. Yet, no confirmed pharmacological, biological or surgical therapy could prevent the progressive destruction of OA joint. Mesenchymal stem cells (MSCs) with immunosuppressive activities emerged a potential therapy. We describe a magnetic resonance images (MR...

In this study, our aim was to produce a generation of GMP-grade adipose tissue-derived mesenchymal stem cells for clinical applications. According to our results, we fulfill to establish consistent and also reproducible current good manufacturing practice (cGMP) compliant adipose tissue-derived mesenchymal stem cells from five female donors. The isolated cells were cultured in DMEM supplemented...