Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats


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Fenitrothion induced oxidative stress and morphological alterations of sperm and testes in male sprague-dawley rats

OBJECTIVE Fenitrothion residue is found primarily in soil, water and food products and can lead to a variety of toxic effects on the immune, hepatobiliary and hematological systems. However, the effects of fenitrothion on the male reproductive system remain unclear. This study aimed to evaluate the effects of fenitrothion on the sperm and testes of male Sprague-Dawley rats. METHODS A 20 mg/kg...

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Effect of Vitamin C and Vitamin E on Mercuric Chloride -Induced Reproductive Toxicity in Male Rats

Mercury is a naturally occurring metal, which can exist in several forms. Metallic mercury is a shiny, silver-white, odorless liquid, which forms a colorless, odorless gas if heated. Mercury combines with other elements such as chlorine, sulfur, or oxygen to form inorganic mercury compounds or salts, which are usually white solids. Mercury also combines with carbon to make organic mercury compo...

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Protective effects of aqueous extract of M. Pruriens Linn. (DC) seed against gentamicin induced oxidative stress and nephrotoxicity in rats

In the present study, we investigated the effects of the aqueous extract of Mucuna pruriens against gentamicin (100 mg kg -1 per day for six days) induced oxidative stress and nephrotoxicity in rats. Administration of gentamicin to rats induced a marked renal failure, characterized by a significant increase in urine volume and serum creatinine and urea levels. There was a significant decr...

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Role of Tribulus terrestris (Linn.) (Zygophyllacea) against mercuric chloride induced nephrotoxicity in mice, Mus musculus (Linn.).

The present study investigates the influence of methanolic fraction (MF) of Tribulus terrestris fruit extract on the kidney tissues of mercury intoxicated mice, Mus musculus. At median-lethal dose of mercuric chloride (12.9 mg/kg body weight), the whole kidney tissue showed an increased level of lipid peroxidation (LPO), glutathione peroxidase (GPx) activities and simultaneously a decreased lev...

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Protective effect of Rheum turkestanicum root against mercuric chloride-induced hepatorenal toxicity in rats

Objective: The present study was designed to investigate the protective effects of hydroalcoholic extract of Rheum turkestanicum against HgCl2 hepatorenal toxicity in rats. Materials and Methods: Animals were randomly divided into five groups (n= 6 in each group) and received HgCl2 and plant’s extract, intraperitoneally. Group1 received saline (1 mL/kg/day), group 2 received extract (200 mg/kg/...

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عنوان ژورنال: Environmental Health and Preventive Medicine

سال: 2019

ISSN: 1342-078X,1347-4715

DOI: 10.1186/s12199-019-0820-x