Assessment of Human Sperm Function After Recovery from the Female Reproductive Tract
At coitus, human sperm are deposited into the anterior vagina, where, to avoid vaginal acid and immune responses, they quickly contact cervical mucus and enter the cervix. Cervical mucus filters out sperm with poor morphology and motility and as such only a minority of ejaculated sperm actually enter the cervix. In the uterus, muscular contractions may enhance passage of sperm through the uteri...متن کامل
The ability to store sperm in the female genital tract is frequently observed in vertebrates as well as in invertebrates. Because of the presence of a system that maintains the ejaculated sperm alive in the female reproductive tract in a variety of animals, this strategy appears to be advantageous for animal reproduction. Although the occurrence and physiological reasons for sperm storage have ...متن کامل
Expression of cystatin C in the female reproductive tract and its effect on human sperm capacitation
BACKGROUND Cystatin C (CST3), a cysteine protease inhibitor in seminal plasma, is expressed in animal uteri. However, its expression in the human female reproductive tract and its effect on human sperm capacitation are unclear. METHODS The cellular localization of CST3 was observed using immunohistochemistry. The binding of CST3 to sperm was examined using immunocytochemistry. Sperm motility ...متن کامل
A glimpse at sperm function in vivo: sperm transport and epithelial interaction in the female reproductive tract.
The process of sperm transport in the female reproductive tract is more than simply a migration of spermatozoa from the site of insemination to the site of fertilization. Rather, it is a complex and dynamic continuum that encompasses phases of sperm distribution within the tract, the accumulation of spermatozoa in reservoirs, the modulation of sperm physiology and acquisition of fertilization c...متن کامل
Do sperm possess a molecular passport? Mechanistic insights into sperm selection in the female reproductive tract.
Most male mammals produce far more spermatozoa on a daily basis than is strictly necessary for reproduction and females have evolved mechanisms that prevent all but a small minority from reaching the vicinity of their oocytes. One potential explanation for the stringent selection is that females have developed these mechanisms as a way of avoiding polyspermy as well as exercising post-copulator...متن کامل
عنوان ژورنال: Biology of Reproduction