Bayesian inference of protein structure from chemical shift data
نویسندگان
چکیده
منابع مشابه
Bayesian inference of protein structure from chemical shift data
Protein chemical shifts are routinely used to augment molecular mechanics force fields in protein structure simulations, with weights of the chemical shift restraints determined empirically. These weights, however, might not be an optimal descriptor of a given protein structure and predictive model, and a bias is introduced which might result in incorrect structures. In the inferential structur...
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ژورنال
عنوان ژورنال: PeerJ
سال: 2015
ISSN: 2167-8359
DOI: 10.7717/peerj.861