Chemoenzymatic resolution of rac-malathion

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Chemoenzymatic Kinetic resolution of (R)-malathion in aqueous media

BACKGROUND Malathion (R,S)-diethyl-2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate is a chiral organophosphorus compound used widely as pesticide for suppression of harmful insects such as mosquitoes. It is well known that in biological systems (R)-malathion is the active enantiomer, therefore a sustainable approach could be the use of only the biologically active enantiomer. The resolution ...

متن کامل

Chemoenzymatic Resolution in Dynamic Systems: Screening, Classification and Asymmetric Synthesis

This thesis is divided into four parts, all centered around Constitutional Dynamic Chemistry (CDC) and Dynamic Kinetic Resolution (DKR) using biocatalysts for selective transformations, and their applications in screening of bioactive compounds, organic synthesis, and enzyme classification. In part one, an introduction to CDC and DKR is presented, illustrating the basic concepts, practical cons...

متن کامل

Chemoenzymatic Enantioselective Formal Synthesis of (-)-Gephyrotoxin-223

(-)-Gephyrotoxin-223 was formally synthesized from chiral synthon 1 which has been chemoenzymatically synthesized  in the presence  of Candida Antartica lipase.        

متن کامل

Chemoenzymatic Dynamic Kinetic Resolution: A Powerful Tool for the Preparation of Enantiomerically Pure Alcohols and Amines

Chemoenzymatic dynamic kinetic resolution (DKR) constitutes a convenient and efficient method to access enantiomerically pure alcohol and amine derivatives. This Perspective highlights the work carried out within this field during the past two decades and pinpoints important avenues for future research. First, the Perspective will summarize the more developed area of alcohol DKR, by delineating...

متن کامل

Chemoenzymatic preparation of germacrene analoguesw

Terpenoids represent a valuable class of bioactive fine chemicals and are therefore attractive targets for synthetic modification; modulation of their natural properties may lead to new medicinal and agrochemical compounds with improved properties. However, the complexity of the hydrocarbon skeletons and the often significant chemical instability of many terpenoids can present a formidable chal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Tetrahedron: Asymmetry

سال: 2014

ISSN: 0957-4166

DOI: 10.1016/j.tetasy.2014.02.013