Contamination control.

The Contamination Control Plan in Facility Validation

The contamination control plan is central to good manufacturing practice (GMP) because it describes the procedures and policies designed to create products under controlled conditions. The contamination control plan covers all phases of a facility's status and, therefore, plays a major part in the master validation plan. The author provides an overview of the contamination control plan as it ap...

Control of microbial contamination in unpreserved eyedrops.

AIMS/BACKGROUND Preservatives are added to multidose eyedrop containers to ensure that the eyedrops do not become heavily contaminated during patient use. This enables eyedrops to be used for up to 1 month after opening. However, patients are frequently required to use unpreserved eyedrops as their eyes are unable to tolerate these preservatives. Some commercial unpreserved unit dose eyedrops a...

Contamination Control Study on Mine Dust

In order to ensure that the Sudbury Neutrino Observatory (SNO) is clean, some simple methods need to be developed for the cleanliness monitoring program. Two methods arc selected and examined. The two methods. X-ray fluorescence and optical counting, can be used for detecting and quantifying the amount of mine dust on flat surfaces. X-ray fluorescence is based on element detection, a method tha...

The importance of infection and contamination control.

Contamination Control of the SABER Cryogenic Infrared Telescope

The SABER instrument (Sounding of the Atmosphere using Broadband Emission Spectroscopy) is a cryogenic infrared sensor on the TIMED spacecraft with stringent molecular and particulate contamination control requirements. The sensor measures infrared emissions from atmospheric constituents in the earth limb at altitudes ranging from 60 to 180 km using radiatively-cooled 240 K optics and a mechani...