Deoxyribonuclease partially ameliorates thioacetamide-induced hepatorenal injury
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چکیده
منابع مشابه
Sumatriptan ameliorates renal injury induced by cisplatin in mice
Objective(s): Cisplatin (Cis) is an anticancer compound, which is used for the treatment of various cancers. Sumatriptan (Suma) is a selective agonist of 5-hydroxytryptamine 1B/1D (5HT1B/1D) receptor, which is prescribed for the management of migraine. It is well-established that Suma has anti-inflammatory and antioxidant properties. We have explored the protective effe...
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AIM To investigate the effects of cyclosporine A (CsA) on thioacetamide (TAA)-induced liver injury. METHODS CsA was co-administrated (7.5 microg/kg body weight per day, i.p.) into rat to investigate the role of CsA on TAA-(200 mg/kg body weight per 3 d for 30 d, i.p.)induced liver injury. RESULTS The data show that TAA caused liver fibrosis in rat after 30 d of treatment. CsA alleviates the...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2017
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00446.2016