Edirne Yeni Saray’ın Harem Bölümünde H 1171 (M 1757-58) Yılında Yapılan Onarımlar
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Lymphoproliferative disorders are a very heterogeneous group of neoplastic diseases, which originate from malignant transformation of cells of the lymphoid system. Within broad limits, they include at least four main types of diseases: Hodgkin’s disease, the socalled non-Hodgkin’s lymphomas, the chronic lymphoid leukemias and the neoplasms of mature B antibody-producing cells, such as Waldenstr...
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SSc is a heterogeneous autoimmune CTD characterized by widespread vasculopathy, formation of autoantibodies and varying degrees of skin and major organ fibrosis [1, 2]. The life-threatening nature of this disease is well depicted by a 5-year mortality of 30 50% in a subset of patients with dcSSc and internal organ involvement. Despite the substantial research over the past decade, the aetiology...
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Multiple cell types involved in the regulation of angiogenesis express Wnt ligands. Although β-catenin dependent and independent Wnt signaling pathways have been shown to control angiogenesis, the contribution of individual cell types to activate these downstream pathways in endothelial cells (ECs) during blood vessel formation is still elusive. To investigate the role of ECs in contributing Wn...
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Model systems, including laboratory animals, microorganisms, and celland tissue-based systems, are central to the discovery and development of new and better drugs for the treatment of human disease. In this issue, Disease Models & Mechanisms launches a Special Collection that illustrates the contribution of model systems to drug discovery and optimisation across multiple disease areas. This co...
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There are many ways an organization can approach innovation. On one end of the spectrum an organization can choose to have everyone submit any idea. On the other, innovation can be generated from a small, dedicated group of specialists. In the middle there are many variations along the way. This paper discusses the open innovation typology and the options for an organization making the decision...
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ژورنال
عنوان ژورنال: Sanat Tarihi Dergisi
سال: 2020
ISSN: 1300-5707
DOI: 10.29135/std.666714