Electrocardiographic changes in cases of duchenne muscular dystrophy

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Electrocardiographic studies in the patients of Duchenne muscular dystrophy.

Electrocardiographic (ECG) data from twenty Duchenne dystrophic patients aged 6 18 years were examined and compared with normal standards to explore the characteristic ECG abnormalities in these patients. Pathological electrocardiographic patterns were seen in 13 cases whereas 7 electrocardiograms were found normal. Amongst these 13 cases, the ECG of seven patients showed right ventricular hype...

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P164: Adeno-Associated Viral Vectors in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (BMD) is an inherited X-link disease. The incidence of this muscle-wasting disease is 1:5000 male live births. Mutation in the gene coding for dystrophin is the main cause of BMD. Most cases of this disease succumb to respiratory and cardiac failure in 3rd to 4th decades. The slow progression of BMD and recent achievement of gene therapies make it as an appropriate c...

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[Duchenne muscular dystrophy: electrocardiographic analysis of 131 patients].

BACKGROUND Cardiac involvement is known to occur in patients with Duchenne muscular dystrophy (DMD). The electrocardiogram (ECG) shows some typical changes in DMD, which makes it a useful test for the diagnosis of cardiac lesion in this disease. OBJECTIVE To evaluate the electrocardiographic changes in patients with DMD and to correlate these changes with the age of the population studied. ...

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Duchenne muscular dystrophy An overview of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) affects approximately 1 in 3,500 live male births [1]. It is caused by a large variety of mutations in the dystrophin gene. Because of these mutations, the body can no longer make dystrophin which is a protein important for stabilisation of the muscle cell during a contraction. Without dystrophin, muscle cells are damaged and slowly replaced by fat and scar tis...

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Duchenne muscular dystrophy.

Progress in understanding the role of dystrophin raises promising hopes for a treatment for Duchenne muscular dystrophy. In addition, great improvements have been made in the ability to diagnose this disease using simple molecular methods.

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ژورنال

عنوان ژورنال: Journal of the Saudi Heart Association

سال: 2013

ISSN: 1016-7315

DOI: 10.1016/j.jsha.2013.03.137