Enhanced brain delivery of lamotrigine with Pluronic® P123-based nanocarrier
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منابع مشابه
Enhanced brain delivery of lamotrigine with Pluronic® P123-based nanocarrier
BACKGROUND P-glycoprotein (P-gp) mediated drug efflux across the blood-brain barrier (BBB) is an important mechanism underlying poor brain penetration of certain antiepileptic drugs (AEDs). Nanomaterials, as drug carriers, can overcome P-gp activity and improve the targeted delivery of AEDs. However, their applications in the delivery of AEDs have not been adequately investigated. The objective...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2014
ISSN: 1178-2013
DOI: 10.2147/ijn.s62263