Esophageal Cancer: Esophageal Cancer Drug Therapy

Esophageal Cancer Radiation Therapy

Esophageal cancer often is asymptomatic until it has advanced or metastasized to distant organs, limiting treatment options. The 2 most common forms are squamous cell carcinomas that appear in the upper or midesophagus and esophageal adenocarcinomas that tend to occur lower in the esophagus or at the gastroesophageal junction. Since the 1980s higher rates of esophageal adenocarcinomas have been...

Radiation therapy and esophageal cancer.

BACKGROUND Squamous cell carcinoma and adenocarcinoma account for more than 90% of all esophageal cancer cases. Although the incidence of squamous cell carcinoma has declined, the incidence of adenocarcinoma has risen due to increases in obesity and gastroesophageal reflux disease. METHODS The authors examine the role of radiation therapy alone (external beam and brachytherapy) for the manage...

Multimodality Therapy for Esophageal Cancer.

Adjuvant and neoadjuvant therapeutic principles have in recent years received increasing attention in the management of patients with esophageal cancer. A series of randomized prospective trials has convincingly demonstrated that adjuvant postoperative radiation or chemotherapy does not result in a survival advantage after a complete tumor resection. The available data on the role of neoadjuvan...

Multimodality therapy for esophageal cancer.

Recent developments in the epidemiology, staging, and treatment of esophageal and gastroesophageal junction cancers have led to significant changes in the way these malignancies are managed. Although a relationship between gastroesophageal reflux disease and esophageal cancer has been demonstrated, antireflux surgery has been shown to have no preventive effect with regard to the development of ...

Esophageal Cancer