Estrogen

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Good Estrogen Bad Estrogen

Estrogen is a term used for a variety of natural and synthetic hormones that influence the growth and function of many tissues, particularly those of the male and female reproductive systems. Estrogen plays a role in several cancers, especially breast and endometrial cancers and possibly prostate and colon cancers. The human diet contains estrogenic compounds that can bind to estrogen receptors...

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Effects of treadmill exercise training on cerebellar estrogen and estrogen receptors, serum estrogen, and motor coordination performance of ovariectomized rats

Objective(s): The present study aims at examining the motor coordination performance, serum and cerebellar estrogen, as well as ERβ levels, of ovariectomized rats (as menopausal model) following regular exercise. Materials and Methods:Ten female Sprague Dawley ratsaged 12 weeks old were randomly divided into two groups; all of which underwent ovariectomy. The first group was treated with regula...

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Estrogen receptor interaction with estrogen response elements.

The estrogen receptor (ER) is a ligand-activated enhancer protein that is a member of the steroid/nuclear receptor superfamily. Two genes encode mammalian ER: ERalpha and ERbeta. ER binds to specific DNA sequences called estrogen response elements (EREs) with high affinity and transactivates gene expression in response to estradiol (E(2)). The purpose of this review is to summarize how natural ...

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Estrogen-independent activation of estrogen receptors.

Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as hypertension, diabetes mellitus, obesity, vascular disease, and stroke.2 The growin...

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Estrogen, Estrogen Receptor and Lung Cancer

Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the mechanistic relationship between the ER and ...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2014

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.113.02500