Extracorporeal artificial liver support in hypoxic liver injury
نویسندگان
چکیده
منابع مشابه
Artificial liver support systems.
Though artificial support systems for kidney failure have been widely available for the past several decades, it is only recently that they have become a promising treatment modality for liver failure. The various liver support systems include conventional dialysis, charcoal hemoperfusion, high volume plasma exchange, liver dialysis using sorbent technology, molecular readsorption recirculating...
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Given that liver failure continues to pose an enormous clinical challenge, the concept of hepatic dialysis has enjoyed significant interest. In particular, many investigations have examined the therapeutic mechanisms and efficacy of artificial albumin dialysis based systems in acute on chronic liver failure, the results of which have been conflicting. Albumin dialysis systems do not appear to s...
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HEPATIC OXYGEN METABOLISM 258 VULNERABILITY OF LIVER TO HYPOXIC AND ISCHEMIC INJURY 259 CELLULAR CHANGES IN HYPOXIA 259 ADENOSINE TRIPHOSPHATE DEPLETION AND HYPOXIC HEPATOCELLULAR NECROSIS 260 PROTECTION BY ACIDOTIC PH AGAINST HYPOXIC KILLING OF LIVER CELLS 261 THE PH PARADOX IN EARLY ISCHEMIA/REPERFUSION INJURY 262 THE MITOCHONDRIAL PERMEABILITY TRANSITION IN REPERFUSION INJURY 262 REACTIVE OX...
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We report a case of a 26-year-old man with no significant medical history, who presented with fatigue, pruritus, jaundice, dark urine and clay colored stool for one month. He had been taking methyl-1-etiochoenolol-epietiocholanolone, an androgenic anabolic steroid (AAS). He was initially found to have a total bilirubin (Tbili) of 6 mg/dL. He discontinued the AAS but the patients' symptoms worse...
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Correspondence to: Dr R Jalan, Liver Failure Group, Institute of Hepatology, University College London Medical School and University College London Hospitals, 69-75 Chenies Mews, London WC1E 6HX, UK; [email protected] _________________________ T his present review is timely with the increasing use of the molecular adsorbents recirculating system (MARS) for the management of liver failure, with ...
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ژورنال
عنوان ژورنال: Liver International
سال: 2011
ISSN: 1478-3223
DOI: 10.1111/j.1478-3231.2011.02583.x