Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior
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چکیده
منابع مشابه
Elevation of p11 in Lateral Habenula Mediates Depression-Like Behavior
The lateral habenula (LHb) is a key brain region involved in the pathophysiology of depression. It is activated by stimuli associated with negative experiences and is involved in encoding aversive signals. Hyperactivity of LHb is found in both rodent models of depression and human patients with depression. However, little is known about the underlying molecular mechanisms. Here we show that in ...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2016
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2016.01.009