منابع مشابه
Helicobacter pylori overcomes natural immunity in repeated infections
Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially thera...
متن کاملUpdate on HIV/SIV infections in Cameroon.
The high degree of human immunodeficiency virus type 1 (HIV-1) diversity in the Cameroonian population indicates a relatively old epidemic in this country. However, studies of pygmy 'hunter-gatherers' show only rare HIV-1 infection, mainly after contact with Bantus rather than from contact with non-human primates.
متن کاملInnate Lymphoid Cells in HIV/SIV Infections
Over the past several years, new populations of innate lymphocytes have been described in mice and primates that are critical for mucosal homeostasis, microbial regulation, and immune defense. Generally conserved from mice to humans, innate lymphoid cells (ILC) have been divided primarily into three subpopulations based on phenotypic and functional repertoires: ILC1 bear similarities to natural...
متن کاملNatural Hosts of SIV Infection
Presentations at the 9th Conference on Retroviruses and Opportunistic Infections, held in Seattle, February 24 to 28, 2002, continued to shed light on the complex interactions between HIV and the immune system. Major topics of discussion included natural hosts of simian immunodeficiency virus (SIV) infection, the dynamics of T lymphocytes, the myriad mechanisms utilized by HIV to avoid host imm...
متن کاملEnhancing SIV-Specific Immunity In Vivo by PD-1 Blockade
Chronic immunodeficiency virus infections are characterized by dysfunctional cellular and humoral antiviral immune responses. As such, immune modulatory therapies that enhance and/or restore the function of virus-specific immunity may protect from disease progression. Here we investigate the safety and immune restoration potential of blockade of the co-inhibitory receptor programmed death 1 (PD...
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ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 2009
ISSN: 0954-6820,1365-2796
DOI: 10.1111/j.1365-2796.2008.02049.x