Immunogenicity and Reactogenicity of an Indigenous Combined Diphtheria, Tetanus, Whole-cell Bordetella pertussis and Hepatitis B Vaccine in Indian Infants
Immunogenicity and reactogenicity of an indigenous combined diphtheria, tetanus, whole-cell Bordetella pertussis and hepatitis B vaccine in Indian infants.
We evaluated the immunogenicity and reactogenicity of diphtheria, tetanus, whole-cell pertussis and hepatitis B (DTPw-HB) combination vaccine manufactured by Shantha Biotechnics Pvt Ltd, Hyderabad, India in healthy infants between 6 and 8 weeks of age. Overall 123 infants (male:female ratio, 1:1.3) were recruited, of which 112 received all three doses of the vaccine at 6, 10 and 14 weeks of age...متن کامل
Immunogenicity and safety of combined diphtheria tetanus whole cell pertussis hepatitis B/ Haemophilus influenzae type b vaccine in Indian infants.
OBJECTIVE To evaluate the immunogenicity of the Hepatitis B and Haemophilus influenzae type b components and the overall safety and reactogenicity of the DTPw-HBV/Hib vaccine when given as primary vaccination to Indian infants. DESIGN AND METHODS At 3 centers in India, 225 healthy infants (who had received HBV at birth) received three doses of DTPw-HBV/Hib vaccine at 6, 10 and 14 weeks of age...متن کامل
Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children
Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured DTwP vaccine administered to preschool children in a number of health centers of Tehran in 2...متن کامل
short term reactogenicity of a triple diphtheria-tetanus-whole cell pertussis vaccine in iranian infants
background: immunization against diphtheria, tetanus and pertussis (dtp) has long been applied in iran using whole cell vaccine. despite the role of whole cell dtp (dtwp) vaccine in reduction of mortality as a result of disastrous diseases such as diphtheria, tetanus, and pertussis, serious local and systemic complications have been attributed to these vaccines. this study was performed to det...متن کامل
Immunogenicity, reactogenicity and consistency of production of a Brazilian combined vaccine against diphtheria, tetanus, pertussis and Haemophilus influenzae type b.
A randomized, double-blinded study evaluating the immunogenicity, safety and consistency of production of a combined diphtheria-tetanus-pertussis-Haemophilus influenzae type b vaccine entirely produced in Brazil by Bio-Manguinhos and Instituto Butantan (DTP/Hib-BM) was undertaken. The reference vaccine had the same DTP vaccine but the Hib component was produced using purified materials supplied...متن کامل
عنوان ژورنال: Journal of Tropical Pediatrics