Immunohistochemical characterisation of the hepatic stem cell niche in feline hepatic lipidosis: a preliminary morphological study

Immunohistochemical evaluation of the activation of hepatic progenitor cells and their niche in feline lymphocytic cholangitis

Objectives The aim of the study was to compare the hepatic progenitor cell niche in healthy feline livers and the liver tissue of cats with lymphocytic cholangitis. Methods Immunohistochemical stainings for vimentin, laminin, beta (β)-catenin and Notch1 intracellular domain (NICD) were used on formalin-fixed liver biopsies from affected (n = 12) and unaffected cats (n = 2). Results All immunohi...

Hepatic Lipidosis in Reptiles

1) Fat or too plentiful diets (associated to obesity and increased abdominal fat bodies). Diagnosed in badly fed crocodiles, lizards and turtles (Maccolini 2010). 2) Reduced activity. Absence of exercise. Diagnosed in monitors and turtles (Stahl 2003). 3) Physiologic disorder. Lack of hibernation. Lack of reproduction. Diagnosed in tortoises and iguanas. 4) Chronic hyporexia and stress. It decr...

Skin fragility syndrome in a cat with feline infectious peritonitis and hepatic lipidosis.

A 6-year-old spayed female domestic shorthair cat with a 3-week history of inappetence, weight loss, and hiding was examined. A palpable abdominal fluid wave, dehydration, and a small tear on the left flank were noted during initial examination. When the cat was gently restrained for blood sampling, the skin on the dorsal neck tore, leaving a 15 cm x 7 cm flap of skin. Clinicopathological abnor...

Clinical application of computed tomography for the diagnosis of feline hepatic lipidosis.

The usefulness of computed tomography (CT) for the diagnosis of feline hepatic lipidosis (FHL) was evaluated. Liver CT number was 54.7+/-5.6 HU (mean+/-SD) in 26 healthy cats. We fast 6 healthy cats for 72 hr to induced FHL experimentally and the cats were assessed by CT and serum biochemical analysis. Liver CT number of the six cats was 53.8+/-3.0 HU before fasting, 46.8+/-2.4 HU after fasting...

The 5 th Annual Vet Education International Online Veterinary Conference “ Feline Hepatic Lipidosis ”