Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss
Association between histone deacetylases and the loss of cochlear hair cells: Role of the former in noise-induced hearing loss.
Noise-induced hearing loss (NIHL) is one of the most frequent disabilities in industrialized countries. It has been demonstrated that hair cell loss in the auditory end organ may account for the majority of ear pathological conditions. Previous studies have indicated that histone deacetylases (HDACs) play an important role in neurodegenerative diseases, including hearing impairment, in older pe...متن کامل
This paper presents noise problems associated with the use of air-turbine drills in dental practice. Two hundred and fifty dentists (male and female) were randomly selected from the faculty of dentistry as well as the dentists who worked private in Tehran. The results indicated that the mean value of sound pressure level produced by the high-speed drills was 69.1 db. Most of the energy from...متن کامل
conclusions despite rising figures of reported occupational hearing loss, working nbii statistics show that the nihl problem in the danish work environment has, in fact, decreased. in our study, we found that roughly one third (around 100 cases) of the 272 screened persons presumably had nihl, taking into account 88 probable cases (column b) and 44 questionable ones (column c + 16 ski slopes). ...متن کامل
OBJECTIVES To review the evidence suggesting that occupational hearing conservation programs prevent noise-induced hearing loss; to describe the features, prevalence, and handicap associated with noise-induced hearing loss; and to describe the otolaryngologist's role in prevention of noise-induced hearing loss. DATA SOURCES Recent statements from the American College of Occupational Medicine,...متن کامل
Introduction: Exposure to hazardous noise induces one of the forms of acquired and preventable hearing loss that is noise-induced hearing loss (NIHL). Considering oxidative stress as the main mechanism of NIHL, it is possible that myricetin can protect NIHL by its antioxidant effect. Therefore, the present study aimed to investigate the preventive effect of myricetin on NIHL. <br /...متن کامل
عنوان ژورنال: Journal of the Association for Research in Otolaryngology