Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model

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Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model

A recent work by Kruse et al. [1], carried out to verify whether CIN 3 lesions are a “matter of co-existence or true progression”, demonstrated a higher prognostic accuracy of Ki67 quantitation over the histopathological classification of uterine cervix intraepithelial neoplasia. The authors specify that the prognostic value consists in the prediction of progression of CIN 1 and 2 lesions to CI...

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Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model

This study of early CIN biopsies (25 CIN1 and 65 CIN2) with long follow-up was done to validate, in a new group of patients, the value of Ki67 immuno-quantitative features to predict high CIN grade in a follow-up biopsy (often denoted to as "progression"), as described in a previous study. Each biopsy in the present study was classified with the previously described Ki67-model (consisting of th...

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ژورنال

عنوان ژورنال: Analytical Cellular Pathology

سال: 2004

ISSN: 2210-7177,2210-7185

DOI: 10.1155/2004/108305