Liver transplantation for adult polycystic liver disease

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Liver transplantation for adult polycystic liver disease.

Polycystic liver disease, commonly associated with polycystic kidney disease, can result in massive hepatomegaly and debilitating symptoms. Surgical intervention for symptomatic polycystic liver disease has been associated with significant morbidity and inconsistent long-term palliation; it is more appropriate in patients with a single dominant cyst or cysts which is/are confined to one lobe. A...

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Liver transplantation for polycystic liver disease.

Polycystic liver disease (PLD) may provoke massive hepatomegaly and severe physical and social handicaps. Data on orthotopic liver transplantation (OLT) for PLD are rare and conflicting. Conservative surgery (resection or fenestration) is indicated for large single cysts, but its value for small diffuse cysts is questionable. In addition, conservative surgery is not devoid of morbidity and mort...

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[Orthotopic liver transplantation in polycystic liver disease].

INTRODUCTION There is currently no effective medical therapy for polycystic liver (PCL). Cyst puncture and sclerotherapy, cyst fenestration, or partial hepatic resections have been used as palliative treatments. Orthotopic liver transplantation (OLT) has become the treatment of choice for terminal PCL, being indicated in patients with limiting symptoms not susceptible to any other medical treat...

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Liver transplantation in patients with polycystic liver disease.

Chronic and end-stage liver diseases negatively affect many aspects of patients’ physical functioning and quality of life. Orthotopic liver transplantation (OLT) is the standard of care for patients with end-stage liver disease and has been shown to improve patients’ survival and health-related quality of life (HRQL). Although the deterioration of hepatic function and the development of complic...

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Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges

Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health problem worldwide. NAFLD is a continuum of disease ranging from mild liver steatosis to severe steatohepatitis, which will ultimately lead to end-stage liver disease with high morbidity and mortality rates. This disorder is considered as a silent liver disease. The metabolic syndrome and its components are accounted as the ...

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ژورنال

عنوان ژورنال: Hepatology

سال: 1998

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.510280218