Malathion-increased Hepatotoxicity in Diabetic Rats
نویسندگان
چکیده
منابع مشابه
Increased Serum Superoxide Dismutase and Catalase Activities in Streptozotocin-Induced Diabetic Rats
Abstract Background and Objective: One of the diabetes complications is the tissue damage caused by the imbalance of oxidants and antioxidants (oxidative stress). The aim of the present study was to evaluate the activity of two antioxidant enzymes -superoxide dismutase and catalase- in the serum of streptozotocin-induced diabetic rats. Material and Methods: This investigation was conduct...
متن کاملPhorate Induced Hepatotoxicity in Rats
Organophosphorus compounds induce oxidative stress leading to generation of free radicals and alterations in antioxidant and scavengers of oxygen free radicals. The present study demonstrates the effect of chronic exposure of phorate in causation of oxidative stress in male Sprague-Dawley rats. Phorate was administered orally at doses 0.05, 0.1 and 1 mg/kg of body weight for 60 days. After the ...
متن کاملIncreased Intraretinal PO2 in Short-Term Diabetic Rats
In diabetic retinopathy, neovascularization is hypothesized to develop due to hypoxia in the retina. However, evidence for retinal hypoxia is limited, and the progressive changes in oxygenation are unknown. The objective of this study was to determine if retinal hypoxia occurs early in the development of diabetes. Intraretinal oxygen (PO2) profiles were recorded with oxygen-sensitive microelect...
متن کاملIncreased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmaceutical and Biomedical Research
سال: 2020
ISSN: 2423-4494,2423-4486
DOI: 10.18502/pbr.v6i1.3428