Mapping crystalline molecular geometries to the conformational energy landscape
نویسندگان
چکیده
منابع مشابه
Mapping the Conformational Landscape of a Dynamic Enzyme
33 Determining the interconverting conformations of dynamic proteins in atomic detail is a major challenge for 34 structural biology. Conformational heterogeneity in the active site of the dynamic enzyme cyclophilin A (CypA) 35 has been previously linked to its catalytic function, but the extent to which the different conformations of these 36 residues are correlated is unclear. Here we compare...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2013
ISSN: 0108-7673
DOI: 10.1107/s010876731309870x