Mapping odorant receptors in neural space
نویسندگان
چکیده
منابع مشابه
Tuning Insect Odorant Receptors
Citation: Wicher D (2018) Tuning Insect Odorant Receptors. Front. Cell. Neurosci. 12:94. doi: 10.3389/fncel.2018.00094 Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor contacts. This article presents a cu...
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The Question The first time I thought about olfaction was when I read a 1985 paper from Sol Snyder's group that discussed the unsolved question of how odors are detected in the nose (Pevsner et al., 1985). This paper opened up a fascinating new world for me. It was estimated that humans could perceive 10,000 or more chemicals as having distinct odors. Even more remarkably, subtle changes in an ...
متن کاملInsect Odorant Receptors: Channeling Scent
Odorant detection in insects involves heterodimers between an odorant receptor (OR) and a conserved seven-transmembrane protein called Or83b, but the exact mechanism of OR signal transduction is unclear. Two recent studies in Nature (Sato et al., 2008; Wicher et al., 2008) now reveal that these OR-Or83b heterodimers form odorant-gated ion channels, revealing a surprising new mode of olfactory t...
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متن کاملSelectivity of odorant receptors in insects
Insect olfactory receptors (ORs) detect chemicals, shape neuronal physiology, and regulate behavior. Although ORs have been categorized as "generalists" and "specialists" based on their ligand spectrum, both electrophysiological studies and recent pharmacological investigations show that ORs specifically recognize non-pheromonal compounds, and that our understanding of odorant-selectivity mirro...
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ژورنال
عنوان ژورنال: Flavour
سال: 2014
ISSN: 2044-7248
DOI: 10.1186/2044-7248-3-s1-o13