منابع مشابه
Association Between Metformin Therapy and Mortality After Breast Cancer
OBJECTIVE Metformin has been associated with a reduction in breast cancer risk and may improve survival after cancer through direct and indirect tumor-suppressing mechanisms. The purpose of this study was to evaluate the effect of metformin therapy on survival in women with breast cancer using methods that accounted for the duration of treatment with glucose-lowering therapies. RESEARCH DESIG...
متن کاملMetformin Associated With Lower Cancer Mortality in Type 2 Diabetes
OBJECTIVE Several studies have suggested an association between specific diabetes treatment and cancer mortality. We studied the association between metformin use and cancer mortality in a prospectively followed cohort. RESEARCH DESIGN AND METHODS In 1998 and 1999, 1,353 patients with type 2 diabetes were enrolled in the Zwolle Outpatient Diabetes project Integrating Available Care (ZODIAC) s...
متن کاملErratum to: Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and..
Aims/hypothesis Observational studies suggest that metformin may reduce cancer risk by approximately onethird. We examined cancer outcomes and all-cause mortality in published randomised controlled trials (RCTs). Methods RCTs comparing metformin with active glucoselowering therapy or placebo/usual care, with minimum 500 participants and 1-year follow-up, were identified by systematic review. Da...
متن کاملAssociation between Metformin Therapy and Breast Cancer Incidence and Mortality: Evidence from a Meta-Analysis
PURPOSE Metformin may be associated with a decreased risk of breast cancer. We performed a meta-analysis to assess the effect of metformin intake on breast cancer risk and mortality. METHODS We performed a PubMed and EMbase search for all available studies that described the risk of breast cancer and all-cause mortality in relation to the use of metformin among patients with type 2 diabetes m...
متن کاملMetformin use and mortality in ambulatory patients with diabetes and heart failure.
BACKGROUND Despite the common coexistence of diabetes and heart failure (HF), the optimal medial treatment of diabetes in HF patients has not been well studied. We sought to compare the association between metformin use and clinical outcomes in a cohort of ambulatory patients with diabetes and established HF. METHODS AND RESULTS Using propensity score-matched samples, we examined the associat...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2013
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-013-2843-y