Multidrug Resistance Protein 2 Implicates Anticancer Drug-Resistance to Sorafenib
نویسندگان
چکیده
منابع مشابه
Multidrug resistance protein 2 implicates anticancer drug-resistance to sorafenib.
Sorafenib and sunitinib is a small molecule inhibitor of certain receptor tyrosine kinases, and have improved outcomes for patients with advanced renal cell carcinoma. Inhibitory concentration of 50% cell growth of sorafenib significantly rose to 6.4-fold in a multidrug resistance protein 2 (MRP2) transfected cell line versus control cell line. The concentration of sorafenib was significantly d...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2011
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.34.433