Neurophysiology of the BOLD fMRI Signal in Awake Monkeys
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چکیده
منابع مشابه
Neurophysiology of the BOLD fMRI Signal in Awake Monkeys
BACKGROUND Simultaneous intracortical recordings of neural activity and blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) in primary visual cortex of anesthetized monkeys demonstrated varying degrees of correlation between fMRI signals and the different types of neural activity, such as local field potentials (LFPs), multiple-unit activity (MUA), and single-unit a...
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Introduction Echo-planar imaging (EPI) is a group of fast data acquisition methods commonly used in fMRI studies. It acquires multiple image lines in k-space after a single excitation, which leads to a very short scan time. A well-known problem with EPI is that it is more sensitive to distortions due to the used encoding scheme. Source of distortion is inhomogeneity in the static B0 field that ...
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The difference between awake curarized and alpha-chloralose anesthetized animals was studied with respect to the BOLD signal response in an fMRI experiment. By studying the activation of the cortex upon electrical forepaw stimulation in the same rat, but following consecutively applied curarization and alpha-chloralose anesthesia protocols, it was possible to compare quantitatively the effect o...
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Blood oxygen-level-dependent functional magnetic resonance imaging (BOLD fMRI) has rapidly become a popular technique for the investigation of brain function in healthy individuals, patients as well as in animal studies. However, the BOLD signal arises from a complex mixture of neuronal, metabolic and vascular processes, being therefore an indirect measure of neuronal activity, which is further...
متن کاملeffect of phase-encoding reduction on geometric distortion and bold signal changes in fmri
introduction echo-planar imaging (epi) is a group of fast data acquisition methods commonly used in fmri studies. it acquires multiple image lines in k-space after a single excitation, which leads to a very short scan time. a well-known problem with epi is that it is more sensitive to distortions due to the used encoding scheme. source of distortion is inhomogeneity in the static b0 field that ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2008
ISSN: 0960-9822
DOI: 10.1016/j.cub.2008.03.054