None so blind

None so blind as those who will not see.

Not so Blind a Watchmaker Richard

Structural and operational principles underlying the organization of the vertebrate retina and bacterial flagellar apparatus are reviewed in the context of William Paley’s classic intelligent designer vs. Richard Dawkins’ contemporary “blind watchmaker” interpretations of biological origins and diversity. The significance of inverted retinal microanatomy and retinocytophysiology is diagnosed. I...

Successful therapies for Alzheimer’s disease: why so many in animal models and none in humans?

Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the therapeutic strategies tested (in animal models) have been successful. One also may notice that there is a deficit in translational research, i.e., to take a successful drug in mice and translate it to the patient. Efforts are still focused on novel projects to expand the therapeutic arsenal to "cure mice...

None so deaf. 171st annual oration. Royal Victoria Hospital, Belfast 1st October 1998.

The tradition of the Annual Oration was introduced in the days when almost all clinical studies were carried out in this hospital, to welcome new clinical medical students. The world has changed since then and with it the curriculum, the academic calendar and, more than anything else, medical care. Although we may bemoan many of these changes, few of us would want to go back to medicine as it w...

Not quite so blind: Semantic processing despite inattentional blindness.

We often fail to detect clearly visible, yet unexpected objects when our attention is otherwise engaged, a phenomenon widely known as inattentional blindness. The potentially devastating consequences and the mediators of such failures of awareness have been studied extensively. Surprisingly, however, hardly anything is known about whether and how we process the objects that go unnoticed during ...