Nucleosomal repeat length in active and inactive genes

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Transcribed chromatin exhibits an altered nucleosomal spacing.

The nucleosomal repeat lengths of bulk chromatin and the chromatin of transcriptionally active and inactive genes were analyzed in two mouse cell lines and adult mouse spleens. The adult beta-globin gene exhibits a nucleosomal repeat length approximately 11 base pairs longer than (i) an inactive embryonic globin gene, epsilon y3; (ii) an immunoglobulin heavy chain gene, Cmu; and (iii) the bulk ...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1987

ISSN: 0014-5793

DOI: 10.1016/0014-5793(87)81142-0