Perioperative management of liver surgery—review on pathophysiology of liver disease and liver failure
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چکیده
منابع مشابه
Pathophysiology of pediatric liver disease Liver development
Introduction Liver development requires two linked processes: differentiation of the various hepatic cell types from their embryonic progenitors and the arrangement of those cells into structures that permit the distinctive circulatory, metabolic, and excretory functions of the liver. Primarily through the use of rodent, fish, and frog model systems, many essential regulators of liver developme...
متن کاملLiver Failure and Liver Disease
Cirrhosis with ascites is associated with impaired renal function accompanied by sodium and water retention. Although it has been suggested thatmediators such as nitric oxide play a role in the development of renal failure in this situation, other mechanisms underlying the process are not well understood. This study examined the role of oxidative stress in mediating renal damage during the deve...
متن کاملEndocrine-Manifestations of Cirrhosis and Liver Disease
The liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. For example the liver is, extremely sensitive to changes in insulin or glucagon levels. The liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. Chr...
متن کاملAcetylcysteine and Liver Failure/Fatty Liver Disease
Alcohol-related steatohepatitis is associated with increased oxidative stress, DNA damage, lipotoxicity, and insulin resistance in liver. As inflammation and oxidative stress can promote insulin resistance, effective treatment with antioxidants, for example, N-acetylcysteine (NAC), may restore ethanol-impaired insulin signaling in the liver. Adult male Sprague-Dawley rats were fed for 130 days ...
متن کاملManagement of liver failure.
In considering a patient in liver failure it is important to distinguish between fulminant hepatic failure (FHF) and episodes of acute hepatic decompensation in patients suffering from chronic liver disease (CLD), as the basis for treatment differs. Fulminant hepatic failure has been defined by Trey and Davidson (1970) as encephalopathy developing within 8 weeks of the onset of symptoms in a pa...
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ژورنال
عنوان ژورنال: European Surgery
سال: 2018
ISSN: 1682-8631,1682-4016
DOI: 10.1007/s10353-018-0522-4