Phylogenetic Analysis of Lysozyme C from the Scorpion Mesobuthus eupeus Venom Gland

First transcriptome analysis of Iranian scorpion, Mesobuthus eupeus venom gland

Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyz...

First transcriptome analysis of Iranian scorpion, Mesobuthus eupeus venom gland

Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyz...

Sequence Analysis of Lysozyme C from the Scorpion Mesobuthus Eupeus Venom Glands Using Semi-Nested RT-PCR

BACKGROUND Lysozyme is an antimicrobial protein widely distributed among eukaryotes and prokaryotes and take part in protecting microbial infection. Here, we amplified cDNA of MesoLys-C, a c-type lysozyme from the most common scorpion in Khuzestan Province, Southern Iran. METHODS Scorpions of Mesobuthus eupeus were collected from the Khuzestan Province. Using RNXTM solution, the total RNA was...

sequence analysis of lysozyme c from the scorpion mesobuthus eupeus venom glands using semi- nested rt-pcr

Production of Recombinant Alpha Neurotoxin of Scorpion Venom Mesobuthus eupeus and Analysis of its Immunogenicity

BACKGROUND Scorpion venom is important and rich source of peptides, most of which have been widely used as pharmacological tools for unraveling structure-function relationship of various ion channels. Naturally occurring toxins can be also considered as lead compounds in the development of novel drugs. OBJECTIVES In this context, the scorpion-derived peptide neurotoxins specific to sodium cha...