Portal inflow restriction enhances liver regeneration and decreases liver injury after major liver resection

Liver Resection With Inflow Occlusion

Delva, E., Camus, Y., Nordlinger, B., Honnoun, L., Parc, R., Deriaz, H., Lienhart, A. and Huguet, C. (1989) Vascular Occlusions for Liver Resections Operative Management and Tolerance to Hepatic Ischemia: 142 Cases. Annals o.f Surgery, 209, 211-218. The intraand early postoperative courses of 142 consecutive patients who underwent liver resections using vascular occlusions to reduce bleeding we...

Increased liver regeneration rate and decreased liver function after synchronous liver and colon resection in rats

BACKGROUND The surgical strategy for the treatment of colorectal cancer and synchronous liver metastases remains controversial. The aim of the present study was to investigate the effects of colonic resection on liver function and regeneration in a rat model. METHODS Ninety-six Sprague-Dawley rats were block-randomized into six groups: Group I had a laparotomy performed. Group II had 1 cm col...

Liver regeneration after liver transplantation.

BACKGROUND/PURPOSE The liver has a remarkable capacity to regenerate after injury or resection. The aim of this review is to outline the mechanisms and factors affecting liver regeneration after liver transplantation. METHODS Relevant studies were reviewed using Medline, PubMed and Springer databases. RESULTS A variety of cytokines (such as interleukin-6 and tumor necrosis factor-α), growth...

Liver Regeneration in Rats after Liver Resection and Small-for-size Liver Transplantation from Living Donors

Techniques of Inflow Occlusion for Liver Resection

Limited resection can be a therapeutic approach in patients with cirrhosis with very low remnant hepatic function after resection. In this study, two hilar vascular clamping methods (hilar selective clamping In 13] and hilar lobar clamping method In 8]), which were used for resection ofhepatocellular carcinoma in patients with cirrhosis, were compared based on cardiovascular stability during cl...