Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition
نویسندگان
چکیده
Racemases and epimerases using a deprotonation/reprotonation mechanism are important drug targets have biotechnological applications. This review focuses on the reactivity, mechanism, inhibition of these versatile enzymes.
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ژورنال
عنوان ژورنال: Chemical Society Reviews
سال: 2021
ISSN: ['0306-0012', '1460-4744']
DOI: https://doi.org/10.1039/d0cs00540a