Recurrence of alcoholic liver disease after liver transplantation

Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges

Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health problem worldwide. NAFLD is a continuum of disease ranging from mild liver steatosis to severe steatohepatitis, which will ultimately lead to end-stage liver disease with high morbidity and mortality rates. This disorder is considered as a silent liver disease. The metabolic syndrome and its components are accounted as the ...

Liver Transplantation for Alcoholic Liver Disease

Alcohol consumption, in particular harmful alcohol use related to Alcohol Use Disorders (AUD) accounts for 3.8% of global mortality and 4.6% of Disability-Adjusted Life Years (DALYs) worldwide [1]. A total of 9.5% of alcohol-related DALYs is due to Alcoholic Liver Disease (ALD) [2]. At present alcohol still represents the most common cause of liver cirrhosis in the Western countries [3]. The de...

Orthotopic liver transplantation for alcoholic liver disease.

Alcohol abuse is the most common cause of end-stage liver disease in the United States, but many transplant centers are unwilling to accept alcoholic patients because of their supposed potential for recidivism, poor compliance with the required immunosuppression regimen and resulting failure of the allograft. There is also concern that alcohol-induced injury in other organs will preclude a good...

HCV-Recurrence After Liver Transplantation

Recurrence of hepatitis C after liver transplantation

Recurrence of hepatitis C virus (HCV) infection following liver transplantation is a major source of morbidity and mortality. The natural history of hepatitis C in the transplant setting is shortened. Overall, one third of HCV-infected recipients have developed allograft cirrhosis due to HCV recurrence by the 5th-7th year post-transplantation. The most significant variables which determine dise...