منابع مشابه
RNA Export
RNA export from the nucleus can be divided into two general phases. The first involves ribonucleoprotein (RNP) movement from the site of RNA transcription and RNP assembly to the nuclear pore complex (NPC). Proposed mechanisms for this step include diffusion and motor-driven transport along a nuclear skeleton or matrix (reviewed by Rosbash and Singer, 1993), but definitive support for either hy...
متن کاملNuclear RNA export.
Eukaryotic cells export several different classes of RNA molecule from the nucleus, where they are transcribed, to the cytoplasm, where the majority participate in different aspects of protein synthesis. It is now clear that these different classes of RNA, including rRNAs, tRNAs, mRNAs and snRNAs, are specifically directed into distinct but in some cases partially overlapping nuclear export pat...
متن کاملNuclear RNA export.
RNA export is the process by which RNAs are transported to the cytoplasm after synthesis, processing, and RNP assembly within the nucleus. The primary focus of this review is mRNA export with particular attention paid to the yeast Saccharomyces cerevisiae. Because there is rather little known about mRNA export in general and even less about yeast mRNA export, our thinking about the problem is i...
متن کاملRNA processing and export.
Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript. This processing is represented by modifications of the pre-mRNA and loading of various protein factors. The sum of protein factors that stay wi...
متن کاملNuclear Export of Messenger RNA
Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of processing steps, including capping at the 5' ends, splicing and cleavage/polyadenylation at the 3' ends. During this process, the mRNA associates with a wide variety of proteins, forming a messenger ribonucleoprotein...
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ژورنال
عنوان ژورنال: Cell
سال: 1995
ISSN: 0092-8674
DOI: 10.1016/0092-8674(95)90323-2