Safety of a 5TH Dose of a Diphtheria-Tetanus-Acellular Pertussis Vaccine(Tripedia®)
Effectiveness of adolescent and adult tetanus, reduced-dose diphtheria, and acellular pertussis vaccine against pertussis.
BACKGROUND Pertussis is among the most poorly controlled bacterial vaccine-preventable diseases in the United States. In 2006, a tetanus, reduced-dose diphtheria, and acellular pertussis (Tdap) booster was recommended for adolescents and adults. Tdap vaccines were licensed on the basis of antibody response without vaccine effectiveness data. METHODS From 30 September 2007 through 19 December ...متن کامل
Safety of a tetanus-diphtheria-acellular pertussis vaccine when used off-label in an elderly population.
BACKGROUND Published data on the safety of tetanus-diphtheria-acellular pertussis vaccine (Tdap) in persons aged ≥65 years are limited. This study aims to examine a large cohort of Tdap users ≥65 years for evidence of increased risk of adverse events following vaccination. METHODS A matched cohort study design and a self-controlled case series (SCCS) design were used. The study population was...متن کامل
TO THE EDITOR—We read with interest Koepke et al’s analysis  of Wisconsin Immunization Registry (WIR) and pertussis surveillance databases to determine effectiveness of tetanus-diphtheria-acellular pertussis (Tdap) vaccines. We are familiar with the challenges involved in using such data sources to evaluate the performance of pertussis vaccines, as we have been collaborating since 2008 in a ...متن کامل
Safety and reactogenicity of a low dose diphtheria tetanus acellular pertussis vaccine (Boostrix) in pre-school Indian children.
OBJECTIVE To evaluate the safety and reactogenicity of a reduced-antigen-content combined Diphtheria Tetanus Acellular Pertussis (dTpa) vaccine in Indian preschool children. METHODS GlaxoSmithKline Biologicals combination dTpa vaccine was administered as a single booster dose to 347 children aged 46 years in seven centers across India. All children were subsequently followed up for two weeks ...متن کامل
DESCRIPTION DAPTACEL, Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed, for intramuscular use, manufactured by Aventis Pasteur Limited, is a sterile suspension of pertussis antigens and diphtheria and tetanus toxoids adsorbed on aluminum phosphate in a sterile isotonic sodium chloride solution. After shaking, the vaccine is a white homogeneous cloudy suspension. Each dose...متن کامل
عنوان ژورنال: Pediatric Research