منابع مشابه
Vaccination against Staphylococcus aureus pneumonia.
BACKGROUND Staphylococcus aureus causes serious infections in both hospital and community settings. Attempts have been made to prevent human infection through vaccination against bacterial cell-surface antigens; thus far all have failed. Here we show that superantigens and cytolysins, when used in vaccine cocktails, provide protection from S. aureus USA100-USA400 intrapulmonary challenge. MET...
متن کاملMethicillin-resistant Staphylococcus aureus nosocomial pneumonia.
Affi liations: From the Division of Clinical Science, St. George’s University of London. Financial/nonfi nancial disclosures: The author has reported to CHEST the following confl icts of interest: Dr Jones has received consulting fees and speakers honoraria from GlaxoSmithKline. Correspondence to: Paul W. Jones, PhD, Division of Clinical Science, St. George’s University of London, Cranmer Terr,...
متن کاملVaccine protection against Staphylococcus aureus pneumonia
Staphylococcus aureus pneumonia causes significant mortality in hospitalized or healthy individuals, and recent increases in morbidity are attributed to the rapid spread of methicillin-resistant S. aureus (MRSA) strains, which are often not susceptible to antibiotic therapy. Alpha-hemolysin (Hla), a secreted pore-forming toxin, is an essential virulence factor of MRSA in a mouse model of S. aur...
متن کاملAn antidote for Staphylococcus aureus pneumonia?
Methicillin-resistant Staphylococcus aureus (MRSA) is the leading cause of bacterial infections in the United States. Severe invasive MRSA infections, which include pneumonia, are difficult to treat because the bacteria are resistant to antibiotics. A new report now shows that immunization against alpha-hemolysin (Hla), a cytolytic toxin secreted by most S. aureus strains, protects mice against...
متن کاملMethicillin-resistant Staphylococcus aureus Necrotizing Pneumonia
1. He JZ, Zhu SH, Yang SQ. First discovery and evidence of Angiostrongylus cantonensis in the cerebrospinal fluid from the case of population of mainland of China. J Guangzhou Med Coll. 1984;12:1–4. 2. Xue DY, Ruan YZ, Lin BC. Epidemiological investigation on an outbreak of angiostrongyliasis in Wenzhou. Chin J Parasit Dis. 2000;18:176–8. 3. Lin JX, Li YS, Zhu K. Epidemiological study on group ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Medical Association
سال: 1919
ISSN: 0002-9955
DOI: 10.1001/jama.1919.02610090001001