The continuing evolution of a bacterial pathogen
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چکیده
منابع مشابه
The continuing evolution of a bacterial pathogen.
A lthough Escherichia coli is a prototypic commensal bacterial species of the mammalian intestine and a laboratory workhorse for molecular biology, certain strains of this species are capable of causing significant human disease. The spectrum of disease caused by E. coli includes enteric/diarrheal disease, urinary tract infections, renal failure, and sepsis/meningitis (1). The different pathoty...
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Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity. Molecular arms-races have been a strong driving force for the evolution of pathogenicity, with pathogens often encoding overlapping or redundant functions, such as type III protein secr...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0801435105