The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) instrument was useful for refining a randomized trial design: Experiences from an investigative team
نویسندگان
چکیده
منابع مشابه
A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers.
OBJECTIVE To propose a tool to assist trialists in making design decisions that are consistent with their trial's stated purpose. STUDY DESIGN AND SETTING Randomized trials have been broadly categorized as either having a pragmatic or explanatory attitude. Pragmatic trials seek to answer the question, "Does this intervention work under usual conditions?," whereas explanatory trials are focuse...
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medical care. Methods: In a randomized comparative effectiveness trial, we randomized 107 participants with acute and sub-acute low back pain to: 1) usual medical care; 2) manual side-posture manipulation; and 3) mechanical manipulation (Activator). The primary outcome was self-reported disability (Oswestry) at four weeks. Pain was rated on a 0 to 10 numerical rating scale. Pain and disability ...
متن کاملThe value of the pragmatic-explanatory continuum indicator summary wheel in an ongoing study: the bullous pemphigoid steroids and tetracyclines study
BACKGROUND The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) tool is intended to be used in the design phase of trials to help investigative teams design trials in-line with their purpose. Our team applied this tool to an ongoing trial (BLISTER) to determine whether the initial suggestion among some team members that the trial could be described as largely pragmatic was the consens...
متن کاملA pragmaticeexplanatory continuum indicator summary (PRECIS): a tool to help trial designers
Objective: To propose a tool to assist trialists in making design decisions that are consistent with their trial’s stated purpose. Study Design and Setting: Randomized trials have been broadly categorized as either having a pragmatic or explanatory attitude. Pragmatic trials seek to answer the question, ‘‘Does this intervention work under usual conditions?,’’ whereas explanatory trials are focu...
متن کاملUsing the Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model in clinical research: Application to refine a practice-based research network (PBRN) study.
BACKGROUND Pragmatic clinical trials (PCTs) are increasingly recommended to evaluate interventions in real-world conditions. Although PCTs share a common approach of evaluating variables from actual clinical practice, multiple characteristics can differ. These differences affect interpretation of the trial. The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model was developed in 20...
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ژورنال
عنوان ژورنال: Journal of Clinical Epidemiology
سال: 2010
ISSN: 0895-4356
DOI: 10.1016/j.jclinepi.2010.03.006