منابع مشابه
Type 2 diabetes: new genes, new understanding.
Over the past two years, there has been a spectacular change in the capacity to identify common genetic variants that contribute to predisposition to complex multifactorial phenotypes such as type 2 diabetes (T2D). The principal advance has been the ability to undertake surveys of genome-wide association in large study samples. Through these and related efforts, approximately 20 common variants...
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Inflammatory cytokines increase in patients with type 2 diabetes (T2D) and metabolic syndrome. This review focuses on inflammatory cytokines such as C-reactive protein (CRP), tumor necrosis factor (TNF-α), and adiponectin, a cytokine produced by adipose tissue and associated with insulin sensitivity. Despite the major role of cytokines in the development of T2D, in the case of adiponectin still...
متن کاملPharmacogenomic approach in type 2 diabetes treatment
Introduction: Type 2 diabetes (T2D) is chronic health caused by the interaction between genetic and environmental factors that results in high blood glucose. The evidence-based guidelines for diabetes management are mainly based on lifestyle changes, control of risk factors, and the management of blood glucose levels. Although numerous antidiabetic agents have been developed over time, T2D trea...
متن کاملUnderstanding the rising incidence of type 2 diabetes in adolescence.
T he definition of diabetes mellitus (DM) was recently changed by the American Diabetes Association to a fasting plasma glucose value of at least 126 mg/dl (6.9 mmol/l), on the basis of increased risk of the complication of retinopathy. It has been estimated that worldwide approximately 154 million people have diabetes, with up to one third of the cases remaining undiagnosed in developed countr...
متن کاملRecent advances in understanding/managing type 2 diabetes mellitus
The treatment of type 2 diabetes mellitus has evolved in the present century toward safer and maybe more effective drugs, which in some cases can also reduce the risk of cardiovascular and renal outcomes. Nevertheless, we still need better strategies to reduce excess body weight in order to achieve diabetes remission, which is now a feasible target, as has been demonstrated with bariatric surge...
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ژورنال
عنوان ژورنال: Delaware Journal of Public Health
سال: 2017
ISSN: 2639-6378
DOI: 10.32481/djph.2017.04.005