Vasorelaxant activity of extracts obtained from Apium graveolens: Possible source for vasorelaxant molecules isolation with potential antihypertensive effect
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منابع مشابه
Vasorelaxant effect of Laelia speciosa and Laelia anceps: Two orchids as potential sources for the isolation of bioactive molecules
Jorge Vergara-Galicia, Patricia Castillo-España, Rafael Villalobos-Molina, Samuel Estrada-Soto División de Ciencias de la Salud, Universidad de Quintana Roo, Chetumal, Quintana Roo, México. Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, México. Unidad de biomedicina, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autóno...
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Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
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The present study was performed to evaluate the cardiovascular effects of ethanolic extract from the root bark of Ulmus macrocarpa (RBUM) in rats. The effects of RBUM on the vascular response of isolated rat aorta and the blood pressure of spontaneously hypertensive rats (SHRs) were evaluated. In addition, its antioxidant activity in H9c2 cells was investigated. In the free radical scavenging a...
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Effects of ER-001533 (ER), a newly synthesized vasorelaxant, on the membrane currents were examined in single ventricular cells of guinea pigs. The patch-clamp technique was used in the "whole-cell" and "inside-out" patch configurations. In the whole-cell clamp condition, ER induced a time-independent K'-dominant current, which was inhibited by glibenclamide (1-3 ,uM), suggesting that ER activa...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Biomedicine
سال: 2013
ISSN: 2221-1691
DOI: 10.1016/s2221-1691(13)60154-9