X Chromosome Inactivation: No longer ‘all-or-none’
نویسندگان
چکیده
منابع مشابه
X Chromosome Inactivation in Opioid Addicted Women
Introduction: X chromosome inactivation (XCI) is a process during which one of the two X chromosomes in female human is silenced leading to equal gene expression with males who have only one X chromosome. Here we have investigated XCI ratio in females with opioid addiction to see whether XCI skewness in women could be a risk factor for opioid addiction. Methods: 30 adult females meeting DS...
متن کاملX-chromosome inactivation
It is a well-known fact of popular science that nearly all tortoiseshell cats are female. Underlying this is X-chromosome inactivation, a phenomenon found in all mammals. In the sex-determining system of mammals — in which females carry two X chromosomes and males an X and a Y chromosome — the X chromosome is typically large and carries many genes unconnected with sex, whereas the Y chromosome ...
متن کاملx chromosome inactivation in opioid addicted women
introduction: x chromosome inactivation (xci) is a process during which one of the two x chromosomes in female human is silenced leading to equal gene expression with males who have only one x chromosome. here we have investigated xci ratio in females with opioid addiction to see whether xci skewness in women could be a risk factor for opioid addiction. methods: 30 adult females meeting dsm iv ...
متن کاملX-chromosome inactivation and autoimmunity
We thank Dr Ozcelik for his careful reading of our review and his thoughtful letter. Dr Ozcelik raises the issue of nonequivalence of monosomy X frequency and X-chromosome inactivation pattern (XCIP). The first refers to the proportion of cells with a single X chromosome, wherein transcription occurs from the lone X chromosome. The second refers to the ratio of inactivated maternal to paternal ...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2005
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5201443