X-irradiation attenuates relaxant responses in the rabbit ear artery
نویسندگان
چکیده
منابع مشابه
Electroretinographic responses of the rabbit after x-irradiation.
The inhibitory effects of 250 KVP x-radiation on the electroretinographic response (ERG) of the rabbit were investigated. Rabbits were exposed (head only) to either a single dose ranging from 3,000 rad to 8,000 rad or to a fractionated dose, two doses of 3,000 rod each with an interval of 5 days. ERG responses of the dark adapted eyes of the rabbit were determined prior to exposure and at vario...
متن کاملBiphasic vasoconstriction of the rabbit ear artery.
Sympathetic nerve stimulation and intralummal norepinephrine infusion for more than 15 seconds produced a biphasic response in the isolated rabbit ear artery perfused with RREBS solution. This response consisted of an initial rapid constriction (phase A), which was followed by partial relaxation, and a final slowly developing constriction (phase B), which lasted for the duration of nerve stimul...
متن کاملComparison of constrictor responses of the rabbit ear artery to norepinephrine and to sympathetic nerve stimulation.
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملComparison of Constrictor Responses of the Rabbit Ear Artery to Noreplnephrine and to Sympathetic Nerve Stimulation
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملBiphasic constrictor response of the rabbit ear artery.
The perfused rabbit ear artery shows a biphasic contractile response to intraluminal norepinephrine and sympathetic nerve stimulation. The peak of the first phase occurs after approximately 10 seconds of exposure to NE, and the second, after IK to 2 minutes. The magnitudes of the two responses are similar. The time course of the second phase of contraction is similar to the rate of saturation o...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1992
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1992.tb14222.x