a three dimensional htlv-1 model with intracellular and immune activation delays

نویسندگان

elham shamsara

department of applied mathematics, faculty of mathematical sciences, ferdowsi university of mashhad (fum), mashhad, iran. zahra afsharnezhad

department of applied mathematics, faculty of mathematical sciences, ferdowsi university of mashhad (fum), mashhad, iran. jamal shamsara

pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran.

چکیده

in this paper, a three dimensional mathematical model for htlv-1infection with intracellular delay and immune activation delay is investigated.by applying the frequency domain approach, we show that time delays candestabilize the ham/tsp equilibrium, leading to hopf bifurcations and sta-ble or unstable periodic oscillations. at the end, numerical simulations areillustrated.

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عنوان ژورنال:
journal of mahani mathematical research center

جلد ۵، شماره ۱، صفحات ۳۳-۵۰

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