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چکیده

Benzimidazole derivatives play very efficient role in the medical field with plenty of useful therapeutic activities like antiviral, anti-histaminic, anticancer, antiulcer, antihypertensive, antidiabetic, antifungal, and antimicrobial activity. The potency of these useful derivatives in treatment of microbial infections and including other activities especially anti-carcinogenic encouraged the development of some more potent and pharmacologically efficient compounds. Benzimidazole is outstandingly effective compounds and there are a number of reviews available for biochemical and pharmacological studies which confirmed that these molecules are useful against a wide variety of microorganisms. Benzimidazole and its derivatives have been showing hopeful activity in the treatment of several diseases, for these reasons, they achieved much attention as important pharmacophore and privileged structure in medicinal chemistry. This review summarizes to know about the different derivatives of Benzimidazole with their pharmacological activities.

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تاریخ انتشار 2013