Applications of Chitosan and Chitosan Derivatives in Drug Delivery

نویسندگان

  • Vipin Bansal
  • Pramod Kumar Sharma
  • Nitin Sharma
  • Om Prakash
  • Rishabha Malviya
چکیده

Chitosan is a versatile natural polymer. This article reviewed different aspects of Chitosan that’s including preparation and characterization of Chitosan with their applicability in pharmaceutical formulations. Also, the article included different derivatives of Chitosan and their use in different drug delivery system. This review emphasized that research on Chitosan based systems containing various drugs for various therapeutic applications have increased in recent years. So this article has fullfill the requirement of a review on this naturally derived polymer in present scenario.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Chemically modified chitin and chitosan as biomaterials

Recent studies of the chemical modification of chitin and chitosan are discussed from the viewpoint of biomedical applications. Special emphasis is placed on the role of individual functional groups in applications of modified chitosan. The modifications discussed here include chitosan attached to sugars, dendrimers, cyclodextrins, crown ethers, and glass beads. Among these derivatives, sugar-m...

متن کامل

Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delive...

متن کامل

Chitosan and Chitosan Derivatives in Drug Delivery and Tissue Engineering

Chitosan is a nontoxic, biodegradable, and biocompatible polysaccharide of b(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine. This derivative of natural chitin presents remarkable properties that have paved the way for the introduction of chitosan in the biomedical and pharmaceutical fields. Nevertheless, the properties of chitosan, such as its poor solubility in water or in organic solven...

متن کامل

Preparations, properties and applications of chitosan based nanofibers fabricated by electrospinning

Chitosan is soluble in most acids. The protonation of the amino groups on the chitosan backbone inhibits the electrospinnability of pure chitosan. Recently, electrospinning of nanofibers based on chitosan has been widely researched and numerous nanofibers containing chitosan have been prepared by decreasing the number of the free amino groups of chitosan as the nanofibiers have enormous possibi...

متن کامل

Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications.

Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial and wound-healing activity. Recently, there has been a growing interest in the chemical modification of chitosan in order to improve its solubility and widen its applications. The main chemical modifications o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013