All-or-none switching of transcriptional activity on single DNA molecules caused by a discrete conformational transition

نویسندگان

  • Ayako Yamada
  • Koji Kubo
  • Tonau Nakai
  • Kanta Tsumoto
  • Kenichi Yoshikawa
چکیده

Japan Recently, it has been confirmed that long duplex DNA molecules with sizes larger than several tens of kilo-base pairs (kbp), exhibit a discrete conformational transition from an elongated coil state to a compact globule state upon the addition of various kinds of chemical species that usually induce DNA condensation. In this study, we performed a single-molecule observation on a ____________

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تاریخ انتشار 2004