International Journal of Phytopharmacology
نویسندگان
چکیده
Diabetes mellitus is a metabolic disorder which has emerged as a global public health threat in the present century. The present oral hypoglycemic agents produce undesirable side effects and oxidative stress. Thus there is a need for a safe, cost effective and complementary therapy for Diabetes mellitus. To evaluate the Nitric oxide scavenging activity and Alpha amylase inhibitory activity of Pterocarpus marsupium. The antioxidant activity was determined by nitric oxide radical scavenging activity according to the method of Garrat (1964). Alpha-amylase inhibitory activity was evaluated according to the method of Bernfield (1955). % Inhibition of Nitric Oxide by Pterocarpus marsupium extract at 20, 40, 60, 80, 100μg/ml was 14.24±0.10, 24.43±0.18, 40.22±0.27, 60.87±0.22, 82.25±0.78 respectively. % inhibition of Alpha amylase by extract of Pterocarpus marsupium at 20, 40, 60, 80, 100μg/ml are 22.54±0.18, 30.64±0.52, 40.92±0.56, 56.08±0.07 and 72.25±0.76 respectively. Based on the results we conclude that Pterocarpus marsupium as strong in vitro nitric oxide scavenging activity and alpha amylase inhibitory activity. Thus, Pterocarpus marsupium is a potential antidiabetic agent.
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