Cannabinoids and neuropathic pain.
نویسندگان
چکیده
After a brief overview of the endocannabinoid system (CB receptors, and endocannabinoids) and of the cannabinergic ligands, some general issues related to cannabinoids and pain are commented. Finally, the most important findings regarding cannabinoids and neuropathic pain are discussed in detail.
منابع مشابه
Treatment of Neuropathic Pain: Opioids, Cannabinoids, and Topical Agents - Printer-friendly version
1. To review the mechanisms and eff ects of opioids, cannabinoids, and topical agents in neuropathic pain. 2. To review clinically relevant pharmacokinetics and pharmacodynamics of opioids, cannabinoids, and topical agents in patients with neuropathic pain. 3. To review the clinical evidence for the use of opi-oids, cannabinoids, and topical agents in neuro-pathic pain.
متن کاملCannabinoids for neuropathic pain.
Treatment options for neuropathic pain have limited efficacy and use is fraught with dose-limiting adverse effects. The endocannabinoid system has been elucidated over the last several years, demonstrating a significant interface with pain homeostasis. Exogenous cannabinoids have been demonstrated to be effective in a range of experimental neuropathic pain models, and there is mounting evidence...
متن کاملRecent data on cannabinoids and their pharmacological implications in neuropathic pain
Natural cannabinoids have been used for centuries for their psychotropic properties, but their possible therapeutic implications in analgesia have been recently documented. The present review intended to make an analysis of the neuroanatomy and physiology of the cannabinoid system (receptors, functions, agents acting on these receptors) and of its implications in neuropathic pain. There were al...
متن کاملRecent developments in the therapeutic potential of cannabinoids.
OBJECTIVE To examine the recent evidence that marijuana and other cannabinoids have therapeutic potential. METHODS Literature published since 1997 was searched using the following terms: cannabinoid, marijuana, THC, analgesia, cachexia, glaucoma, movement, multiple sclerosis, neurological, pain, Parkinson, trial, vomiting. Qualifying clinical studies were randomized, double-blind, and placebo...
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ورودعنوان ژورنال:
- Mini reviews in medicinal chemistry
دوره 3 7 شماره
صفحات -
تاریخ انتشار 2003