The calculation of biological assay results by graphic methods; the all-or-none type of response.

I. The Calculation of Biological Assay Results by Graphic Methods. The All-or-None Type of Response. Edwin J. de Beer 1 II. Antithyroid Studies. II. The Goitrogenic Activity oI Some Imidazoles and Benzimidazoles. W. G. Bywater. D. A. McGinty and N. D. Jenesel.. 14 III. The Experimental Basis for the Quantitative Chemotherapy of B. novyi in Mice with a Comparison of Action of Penicillin and Dichlorphenarsine Hydrochloride. Arthur P. Richardson, Harry A. Walker, Prudence Loeb and Irving Miller 23 IV. Distribution and Fate of Penicillin in the Body. Windsor C. Cutting, F. P. Luduefta, Marshall Fiese, Henry W. Elliott and John Field, II.. 36 V. Effect of Various Electrolytes upon the Toxicity of Desoxycorticosterone Acetate. Hans Selye, J. Mintzberg and E. M. Rowley 42 VI. The Blocking Action of the Cinchona Alkaloids and Certain Related Compounds on the Cardio-Inhibitory Vagus Endings of the Dog. Edwin Hiatt, Dugald Brown, Gertrude Quinn and Kurt MacDuffie 55 VII. Isopropyl Alcohol. Acquired Tolerance in Dogs, Rate of Disappearance from the Blood Stream in Various Species, and Effects on Successive Generation of Rats. A. J. Lehman, Henry Schwerma and Eleanor Rickards 61 VIII. Further Observations on the Pressor Action of Optical Isomers of Sympathomimetic Amines. E. E. Swanson, Frank A. Steldt and K. K. Chen 70 IX. The Hydrolysis of Demerol by Liver in vitro. Frederick Bernheim and Mary L. C. Bernheim 74 X. Biological Comparison of Local Anaesthetics. Edith Bulbring and Isabella Wajda 78 XI. Synthetic Substitutes for Atropine. H. R. Ing, G. S. Dawes and Isabella Wajda