Depression, Anxiety, and Quality of Life in Breast Cancer Patients with Depression Receiving Citalopram and Supportive Group Psychotherapy: A Six-month Longitudinal Study

Authors

  • Bijani, Ali Assistant Professor, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
  • Mohammadian Amiri, Farimah General Practitioner, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
  • Moudi, Sussan Associate Professor, Department of Psychiatry, Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
  • Niazifar, Maede PhD Student in Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
  • Nikbakhsh, Novin Associate Professor, Department of Surgery, Cancer Research Center, Babol University of Medical Sciences, Babol, Iran
Abstract:

Background and purpose: Depression is a common psychiatric disorder in patients with breast cancer. This study was performed to follow-up breast cancer patients with depression receiving citalopram and group psychotherapy for six months. Materials and methods: This clinical trial was conducted in 40 breast cancer patients with depressive disorder. Among the patients, 20 received citalopram (20-40 mg/day) and the rest, besides the same dose of citalopram, attended 8 sessions of group psychotherapy. The patients were assessed at baseline and six months later. Hospital Anxiety and Depression Scale (HADS) and WHO-QOL BREF questionnaires were administered. Then treatment outcomes and quality of life were compared between the two groups applying t-test. Results: The mean scores for depression and anxiety were 12.05±2.19 and 13.25±2.90 at baseline which declined to 2.05±2.06 and 4.55±2.42, respectively, after six months (P<0.05). Quality of life score in patients attending group psychotherapy sessions improved significantly after six months (80.86) compared to that at baseline (40.82), while slight changes were observed in the group receiving only citalopram (P<0.001). Conclusion: Citalopram and group psychotherapy were found to be significantly effective after six months on depression, anxiety, and quality of life in breast cancer patients with depressive disorder receiving citalopram.   (Clinical Trials Registry Number: IRCT2015063022991N1)  

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Journal title

volume 29  issue 173

pages  64- 74

publication date 2019-06

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